Solid-phase synthesis of molecularly imprinted nanoparticles for protein recognition.
نویسندگان
چکیده
A solid-phase synthesis approach to prepare molecularly imprinted polymer nanoparticles (MIP-NPs) specific for trypsin is described. The protein is immobilized on a solid support upon which thermoresponsive MIP-NPs are synthesized. The MIP-NPs are released by a simple temperature change, resulting in synthetic antibody mimics exhibiting high specificity and selectivity for trypsin.
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ورودعنوان ژورنال:
- Chemical communications
دوره 49 60 شماره
صفحات -
تاریخ انتشار 2013